ET usually develops very slowly. It can affect people of any age. But it usually affects middle aged and older people. The average age at diagnosis is about 65 years although it can affect children and young adults.
The clinical picture is dominated by a predisposition to vascular occlusive events and hemorrhages. Some patients with ET are asymptomatic, while others may experience。
Thrombocythemia may lead to . Microvascular occlusions. Large vessel thrombosis . Bleeding. Microvascular occlusions involve small vessels of the distal extremities (causing。
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